Imaging diagnostics in bone metastases.

[Imaging diagnostics in bone metastases]. Radiologe. 2017 Jan 27;: Authors: Kintzelé L, Weber MA Abstract Bone metastases are common, can cause a variety of relevant symptoms and are often associated with a poor prognosis. An early and accurate diagnosis is therefore crucial; however, the pattern is very heterogeneous and necessitates good knowledge of the possibilities and limitations of each imaging modality. Magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET/CT) have the highest sensitivity and specificity for detecting bone metastases. Gradient echo and diffusion-weighted sequences are valuable supplements to the MRI protocol in doubtful cases and MRI is particularly suitable for distinguishing osteoporotic from metastatic spinal fractures with a high degree of diagnostic certainty; however, CT is the modality of choice for stability assessment. Reliable imaging parameters to predict therapy response in cases of bone metastases have not yet been elucidated in large clinical trials. The PET/MRI approach has shown promising preliminary results for diagnosis of bone metastases and further studies in larger cohorts are the subject of ongoing studies. PMID: 28130579 [PubMed - as supplied by publisher]
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research

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