Ongoing outbreak of invasive and non-invasive disease due to group A Streptococcus (GAS) type emm66 among homeless and people who inject drugs in England and Wales, January to December 2016.

We report an outbreak of invasive and non-invasive disease due to an unusual type of Streptococcus pyogenes (group A Streptococcus, emm66) among a vulnerable, largely homeless population in southern England and Wales, detected in September 2016. Twenty-seven confirmed cases were subsequently identified between 5 January and 29 December 2016; 20 injected drugs and six reported problematic alcohol use. To date, we have ruled out drug-related vehicles of infection and identified few common risk factors. PMID: 28128090 [PubMed - in process]
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research

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Streptococcus pyogenes or group A streptococcus (GAS) can cause several mild to life-threatening infections. Age, intravenous drug use, problematic alcohol use, immunosuppression and presence of chronic disease (diabetes mellitus, cancer, or HIV) are the main risk factors for invasive disease among adults.1 GAS infections are defined as invasive (iGAS) based on isolation of the pathogen from blood or other sterile sites. Globally, the occurrence of iGAS has increased during the last decade with an estimate incidence from 2 to 4 per 100,000 in developed countries.
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research
We report that a novel emm32.2 genotype emerged in Liverpool in 2010 and identified a specific subset of genes, which could have allowed this novel emm32.2 genotype to persist in a disadvantaged population in the region over a 3-year period.
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Bacteriology Source Type: research
We report an outbreak of invasive and non-invasive disease due to an unusual type ofStreptococcus pyogenes(group AStreptococcus,emm66) among a vulnerable, largely homeless population in southern England and Wales, detected in September 2016. Twenty-seven confirmed cases were subsequently identified between 5 January and 29 December 2016; 20 injected drugs and six reported problematic alcohol use. To date, we have ruled out drug-related vehicles of infection and identified few common risk factors.
Source: Eurosurveillance - Category: Infectious Diseases Source Type: research
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