Indicators of cardiovascular risk in metabolic syndrome: long term follow-up in Italian patients.

CONCLUSION: The follow-up data of a series of Italian patients with and without MetS, clearly indicates that the former have a raised cIMT and their arterial IMT progression is greater and the presence of a larger WHtR is apparently linked to a higher incidence of CV events. PMID: 28128067 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research

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Metabolic syndrome is characterised by a clustering of metabolic risk factors including abdominal obesity, raised triglycerides, lowered HDL cholesterol, hypertension and impaired glucose tolerance. Multifaceted lifestyle interventions including diet and exercise are recommended as the first-line treatment for the metabolic syndrome.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
CONCLUSION: This study shows that MetS does not predict restenosis after CEA. Also, the presence of MetS did not influence patient survival negatively. PMID: 31653610 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
CONCLUSIONS: The findings support the fact that psoriasis patients have a higher incidence of metabolic syndrome. Our study also recommends that psoriasis patients should be regularly monitored for metabolic syndrome complications and its associated risk factors such as hypertension, raised triglyceride, lowered HDL Cholesterol, increased fasting plasma glucose, and waist circumference. PMID: 31595859 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Endocrinology Authors: Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Authors: Gao RY, Hsu BG, Wu DA, Hou JS, Chen MC Abstract Background: Fibroblast growth factor 21 (FGF21) acts as a potent metabolic regulator. Serum FGF21 levels were significantly higher in obesity and type 2 diabetes mellitus (T2DM) populations. The aim of this study was to evaluate the relationship between serum FGF21 levels and metabolic syndrome (MetS) in T2DM patients. Methods: Fasting blood samples were obtained from 126 T2DM patients. MetS and its components were defined according to the diagnostic criteria from the International Diabetes Federation. Serum FGF21 concentrations were measured using a comm...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
ConclusionsOur results suggest that MetS is associated with alterations in FC between the DMN and other regions of the brain. Furthermore, these results indicate that the overall burden of vascular RFs associated with MetS may, in part, contribute to the pathophysiology underlying aberrant FC in the DMN.
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Contributors : R Maeso-Diaz ; J J Lozano ; J Gracia-SanchoSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusNASH is a severe form of NAFLD that can progress to cirrhosis and hepatocellular carcinoma and, its incidence has markedly increased in recent years. Current available animal models fail to reflect the whole spectrum of the disease. We herein designed a Barcelona NASH (BarNa) rat model using the combination of high fat&cholesterol diet with CCl4 inhalation for 10 weeks (NASH) or 24 weeks (NASH-CH). This model reflects the full spectrum of human NASH and present the main c...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Rattus norvegicus Source Type: research
Metabolic syndrome (MetS) is defined as a group of metabolic disorders that together increase a person ’s chance of developing cardiovascular diseases, including stroke. The component disorders that comprise MetS are central obesity, high blood pressure, high blood sugar, high triglycerides, and low high-density lipoprotein cholesterol (HDL-C) [1]. Body mass index (BMI), waist circumference (WC), w aist-hip ratio (WHpR), and waist-height ratio (WHtR) are anthropometric indices that can be used to define abdominal obesity for MetS diagnosis [2].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
CONCLUSIONS: Specific metabolic syndrome components may have modest associations with ovarian cancer. These associations varied in direction and the prevalence of the components influenced the overall association between metabolic syndrome and ovarian cancer. Evaluating metabolic syndrome as a composite exposure could be misleading in ovarian cancer research, but further study of the syndrome components is warranted. PMID: 31495456 [PubMed - as supplied by publisher]
Source: Gynecologic Oncology - Category: Cancer & Oncology Authors: Tags: Gynecol Oncol Source Type: research
Abstract BACKGROUND: The severity of left ventricular (LV) remodelling is only partially related to the severity of aortic valve stenosis; additional factors, including diabetes, insulin resistance, obesity and metabolic syndrome, may play important roles. Epicardial adipose tissue (EAT), now considered as a metabolically active organ, is also linked to these factors. AIM: To analyse the association between EAT volume measured using computed tomography and LV remodelling in a prospective cohort of patients with aortic stenosis. METHODS: Consecutive asymptomatic patients with at least mild degenerative ao...
Source: Archives of Cardiovascular Diseases - Category: Cardiology Authors: Tags: Arch Cardiovasc Dis Source Type: research
Publication date: October 2019Source: Journal of Functional Foods, Volume 61Author(s): Jordi Mayneris-Perxachs, Juan Maria Alcaide-Hidalgo, Esther de la Hera, Josep Maria del Bas, Lluís Arola, Antoni CaimariAbstractMetabolic syndrome (MetS) has become a major public health concern. Because of their numerous health-promoting biological properties, polyphenols are potential candidates to ameliorate MetS and, recently, the incorporation of these compounds into widely consumed foodstuffs has emerged as a potential strategy to enhance their intake. Therefore, we aimed to assess the potential beneficial effects of biscuit...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
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