Rational and design of an individual participant data meta-analysis of spinal manipulative therapy for chronic low back pain —a protocol

DiscussionWe will analyze IPD for LBP trials in which SMT is one of the interventions. IPD meta-analysis has been shown to be more reliable and valid than aggregate data meta-analysis, although this difference might also be attributed to the number of studies that can be used or the amount of data that can be utilized. Therefore, this project may identify important gaps in our knowledge with respect to prognostic factors of treatment effects.Systematic review registration:PROSPEROCRD42015025714
Source: Systematic Reviews - Category: Global & Universal Source Type: research