Pre-elafin is Involved in Ultraviolet-induced Keratinocyte Apoptosis via Pro-caspase-3 Activation Associated with Cystatin-A Down-regulation.

In conclusion, UV phototoxicity-induced pre-elafin inside keratinocytes prior to cornified envelope formation could be involved in UV-induced keratinocyte apoptosis via cystatin-A downregulation resulting in pro-caspase-3 activation.
PMID: 28119996 [PubMed - as supplied by publisher]

Source: Acta Dermato-Venereologica - January 24, 2017 Category: Dermatology Authors: Kim H, Noh M, Bae ON, Lee CH, Lee AY Tags: Acta Derm Venereol Source Type: research