Ecological validity of cost-effectiveness models of universal HPV vaccination: a protocol for a systematic review

DiscussionThe proposed systematic review will be the first to assess the ecological validity of cost-effectiveness studies. In the context of sexually transmitted diseases, when this condition is violated, an error in predicting the protective impact of herd immunity would occur. Hence, a vaccination policy informed on ecologically invalid models would potentially expose boys to a residual risk of contracting HPV-induced malignancies.Systematic review registrationPROSPEROCRD42016034145
Source: Systematic Reviews - Category: Global & Universal Source Type: research