Corrigendum

Corrigendum to: Endothelial repair in stented arteries is accelerated by inhibition of Rho-associated protein kinase [Cardiovasc Res 2016;112:689–701]
Source: Cardiovascular Research - Category: Cardiology Source Type: research

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ConclusionThese findings indicate that FGF6 reduces skeletal muscle atrophy by relying on the ERK1/2 mechanism and enhances the conversion of slow muscle to fast muscle fibers, thereby promoting functional recovery of regenerated skeletal muscle after innervation.
Source: Life Sciences - Category: Biology Source Type: research
We report the successful repair in a 29-year-old man who experienced penetration of the ascending aorta and bronchus by a crossbow bolt. Imaging studies revealed the arrow penetrating the sternum, right lung, ascending aorta and right bronchus, with medias...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Outcomes of arthroscopic instability repairs vary depending on repair techniques and anchor materials. The purpose of this study is to determine the short to mid-term redislocation, resubluxation rate and clinical outcomes following arthroscopic stabilization of nonabsorbable, biologically inert polymer polyether ether ketone (PEEK) suture anchors. This is a retrospective study with 140 patients who underwent arthroscopic anterior stabilization surgery using PEEK (Pushlock) anchors with a mean follow-up of 40 months. Patient ranked pain scores, clinically assessed range of motion and strength testing were collected preoper...
Source: Techniques in Shoulder and Elbow Surgery - Category: Orthopaedics Tags: Research Articles Source Type: research
Conditions:   Degenerative Mitral Valve Disease;   Mitral Valve Regurgitation Intervention:   Device: Transcatheter implantation of chordal repair system Sponsors:   Pipeline Medical;   ClinLogix. LLC Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We present a novel method to identify associations between rates of protein evolution and continuous phenotypes across the entire mammalian phylogeny. Unlike previous analyses that focused on individual species, we treat absolute and relative longevity as quantitative traits and demonstrate that these lifespan traits affect the evolutionary constraint on hundreds of genes. Specifically, we find that genes related to cell cycle, DNA repair, cell death, the IGF1 pathway, and immunity are under increased evolutionary constraint in large and long-lived mammals. For mammals exceptionally long-lived for their body size, w...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
AbstractDysphagia lusoria is rare embryologic defect of the aortic arch vasculature characterized by an aberrant retro-esophageal course of the right subclavian artery (RSA), comprising a vascular sling. This may manifest clinically with symptoms of dysphagia or reflux. Given the rarity of this pathology, there remains uncertainty regarding the most effective treatment algorithm. Vascular decompression procedure surgery is often used to rectify the aberrant vascular morphology. However, a low percentage of aberrant arteries result in trachea-esophageal symptoms. As such, we suggest (1) one must exclude co-morbid esophageal...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
ConclusionsThe utilization of SVF-coated mesh influences the level of angiogenesis during the early onset of tissue healing. Further long-term animal experiments are needed to confirm that this effect correlates with a more robust mesh integration compared to non-SVF-coated mesh.
Source: Hernia - Category: Sports Medicine Source Type: research
ConclusionThe incidence of mesh infection was observed in 4.97% of total 181 cases. To the best of knowledge, this seems to be the first prospective observational carried out in this country. Of the numerous factors studied, the duration of surgery and mesh contamination were the factors found to have statistical significance on the incidence of mesh infection. Although a clear picture to differentiate surgical site infection from acute mesh infection is yet to be obtained, the study provided better understanding of the management as no mesh explantation was required in either of the cases.
Source: Hernia - Category: Sports Medicine Source Type: research
AbstractPurposeTo examine the updated evidence on safety, effectiveness, and outcomes of mesh versus suture elective umbilical hernia (UH) repair and to explore the timely tendency variations favouring one treatment over another.MethodsMEDLINE and CENTRAL databases were consulted. A systematic review, pairwise meta-analysis, and trial sequential analysis (TSA) were conducted.ResultsSix RCTs were included for a total of 742 patients. Overall, 383 (51.6%) underwent mesh, while 359 (48.4%) underwent suture repair. The estimated pooled postoperative recurrence RR was 0.27 (95% CI 0.13 –0.53;p 
Source: Hernia - Category: Sports Medicine Source Type: research
ConclusionsLaparoscopic exploration is an effective and minimally invasive method for managing the late-onset infection which can identify whether internal organ was involved and consult for the further treatment. The approach of mesh removal should be tailored according to the exploration results.
Source: Hernia - Category: Sports Medicine Source Type: research
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