Contact Burn with Blister Formation in Children Treated with Sennosides

Abstract Eight children treated for severe constipation with sennosides unexpectedly developed contact burns with blisters secondary to the use of these laxatives. All patients wore diapers, and the injuries occurred overnight. To avoid this side effect, we recommend that patients treated with sennosides, especially those in diapers, receive the medication at a time that allows for bowel movements to occur during the day and not overnight.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fpde.13068

Source: Pediatric Dermatology - January 22, 2017 Category: Dermatology Authors: Kimberly Cogley, Andrea Echevarria, Catalina Correa, Luis De la Torre ‐Mondragón Tags: Case Report Source Type: research