A novel fission-independent role of dynamin-related protein 1 in cardiac mitochondrial respiration

Conclusion
These results uncover a novel non-canonical function of the fission protein, DRP1 in maintaining or positively stimulating mitochondrial respiration, bioenergetics and ROS signalling in adult cardiomyocyte, which is likely independent of morphological changes.

Source: Cardiovascular Research - January 22, 2017 Category: Cardiology Authors: Zhang, H., Wang, P., Bisetto, S., Yoon, Y., Chen, Q., Sheu, S.-S., Wang, W. Tags: Cardiac biology and remodelling Source Type: research