PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort

Conclusion:
PLA1A2 polymorphism is associated with mortality in participants with HbA1c ranging from 5.5% (37 mmol/mol) to 6.5% (48 mmol/mol). Maintenance of euglycemic control and antiplatelet therapy are therefore regarded as effective primary prevention in this group.

Source: Cardiovascular Diabetology - May 5, 2014 Category: Cardiology Authors: Bernd StratmannTao XuChrista MeisingerBarbara MenartMichael RodenChristian HerderHarald GrallertAnnette PetersWolfgang KoenigThomas IlligHeinz Erich WichmannRui Wang-SattlerWolfgang RathmannDiethelm Tschoepe Source Type: research