Polygonum multiflorum Radix extract protects human foreskin melanocytes from oxidative stress in vitro and potentiates hair follicle pigmentation ex vivo

ConclusionPolygonum multiflorum Radix extract protects in vitro primary human foreskin melanocytes from the deleterious effects of H2O2‐exposure and improves pigmentation within ex vivo human hair follicles, demonstrating the utility of Polygonum multiflorum Radix extract as a potential active ingredient for the protection of melanocytes against premature death. This data provides in vitro mechanistic evidence consistent with existing in vivo studies for the use of Polygonum multiflorum Radix extract as a strategy for the prevention of oxidative‐stress induced hair greying, in line with traditional Polygonum multiflorum Radix uses.This article is protected by copyright. All rights reserved.

Source: International Journal of Cosmetic Science - January 21, 2017 Category: Dermatology Authors: Peggy Sextius, Richard Betts, Ishak Benkhalifa, St éphane Commo, Joan Eilstein, Marco Massironi, Ping Wang, Jean‐Francois Michelet, Jie Qiu, Xuezhu Tan, Severine Jeulin Tags: Original Article Source Type: research