Rabies viruses reveal wiring in transparent brains

Scientists have harnessed rabies viruses for assessing the connectivity of nerve cell transplants: coupled with a green fluorescent protein, the viruses show where replacement cells engrafted into mouse brains have connected to the host neural network. A clearing procedure which turns the brain into a ' glass-like state ' and light sheet fluorescence microscopy are used to visualize host-graft connections in a whole-brain preparation.
Source: ScienceDaily Headlines - Category: Science Source Type: news