Bioprospecting of antimicrobial activity of extracts of endophytic fungi from Bauhinia guianensis.

Bioprospecting of antimicrobial activity of extracts of endophytic fungi from Bauhinia guianensis. Rev Argent Microbiol. 2017 Jan 13;: Authors: Pinheiro EA, Pina JR, Feitosa AO, Carvalho JM, Borges FC, Marinho PS, Marinho AM Abstract Antibiotic resistance results in higher medical costs, prolonged hospital stays and increased mortality and is rising to dangerously high levels in all parts of the world. Therefore, this study aims to search for new antimicrobial agents through bioprospecting of extracts of endophytic fungi from Bauhinia guianensis, a typical Amazonian plant used in combating infections. Seventeen (17) fungi were isolated and as result the methanolic extract of the fungus Exserohilum rostratum showed good activity against the bacteria tested. The polyketide monocerin was isolated by the chromatographic technique, identified by NMR and MS, showing broad antimicrobial spectrum. PMID: 28094064 [PubMed - as supplied by publisher]
Source: Revista Argentina de Microbiologia - Category: Microbiology Tags: Rev Argent Microbiol Source Type: research