Risks for Post-Transplant Skin Cancer Identified Risks for Post-Transplant Skin Cancer Identified
The first U.S. population-based study of skin cancer in organ transplant recipients found the highest risk in patients who are older, male, white and had pre-transplant skin cancer or received a heart or lung transplant, researchers report.Reuters Health Information
The objective of this study was to determine if long term itraconazole use, as antifungal prophylaxis, in lung transplant recipients is an independent risk factor for skin cancer.
This cohort study examines the risk factors for and frequency of nonmelanoma skin cancer in Australian recipients of heart and/or lung transplant recipients over 10 years.
CONCLUSIONS: Both cancer incidence and mortality are remarkably increased after heart transplantation, with the relative incidence most elevated for SCC, lip and other oral cancers, and for NHL. PMID: 30821595 [PubMed - as supplied by publisher]
Rates of de novo skin cancer after lung or heart transplantation are higher when donor and recipient HLA antigens are well matched, a large retrospective study suggests.Reuters Health Information
Conclusion: PTLD is a heterogeneous group of immunodeficiency-associated lymphoproliferative disorders. The overall survival in non-destructive, polymorphic, and monomorphic PTLD were similar. Monomorphic T/NK cell types had inferior outcomes.Figure.DisclosuresMaurer: Morphosys: Research Funding; Nanostring: Research Funding; Celgene: Research Funding. Ansell: Celldex: Research Funding; Merck &Co: Research Funding; Takeda: Research Funding; LAM Therapeutics: Research Funding; Seattle Genetics: Research Funding; Trillium: Research Funding; Bristol-Myers Squibb: Research Funding; Affimed: Research Funding; Regeneron: Res...
This article, unfortunately paywalled, is interesting to note as a mark of the now increasingly energetic expansion of commercial efforts in longevity science. David Sinclair has been building a private equity company to work in many areas relevant to this present generation of commercial longevity science; while I'm not sold on his primary research interests as the basis for meaningful treatments for aging, he is diversifying considerably here, including into senolytics, the clearance of senescent cells demonstrated to produce rejuvenation in animal studies. This sort of approach to business mixes aspects of investing and...
Lung transplant recipients are at very high risk of skin cancer. Omega-3 fatty acids (FAs) are anti-inflammatory and immune-modulating and potentially could reduce this risk. We assessed the feasibility of omega-3 FA supplementation to reduce skin cancer among these patients.
Lung transplant recipients (LTRs) are at very high risk of skin cancer. Omega-3 fatty acids (FAs) are anti-inflammatory and immune-modulating and could potentially reduce this risk. We assessed the feasibility of omega-3 FA supplementation to reduce skin cancer among these patients.
The objectives of the present study are to assess the practice of lung transplant centers regarding the selection of transplant candidates with skin cancer, and a single center outcome of lung transplantation of patients with skin cancer after implementation of ITSCC guideline.
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