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Top 10 healthcare 3D printing events of 2016

2016 was an exciting year for 3D printing in healthcare. Big investments, mergers...Read more on AuntMinnie.comRelated Reading: 3D-printed kidneys change preop surgical planning FDA video explains agency's role in 3D printing 4 steps to high-quality 3D printing for radiology 3D-printed kidney phantom advances SPECT/CT calibration 3D-printed models are accurate for complex lung cancers
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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This study was undertaken to evaluate the renal radioactivity levels of a newly designed 67Ga-labeled antibody fragment with a linkage cleaved by enzymes present on the brush border membrane (BBM) lining the lumen of the renal tubule. EXPERIMENTAL DESIGN: 67Ga-labeled S-2-(4-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid (SCN-Bn-NOTA) was conjugated with an antibody Fab fragment through a Met-Val-Lys linkage (67Ga-NOTA-MVK-Fab) considering that a Met-Val sequence is a substrate of enzymes on the renal BBM and 67Ga-NOTA-Met is excreted from the kidney into the urine. The enzymatic recognition of the...
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Clin Cancer Res Source Type: research
ConclusionThe specificity, overall accuracy, and PPV of whole-body DWIBS are significantly lower than those of18F-FDG PET/CT because of a high incidence of false-positive findings particularly for detecting bone metastasis, whereas whole-body DWIBS shows a similar level of sensitivities for detecting lymph node and bone metastases to those of18F-FDG PET/CT. DWIBS should be carefully used for cancer staging in children because of its high incidence of false-positive findings in skeletons.
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research
A 39-year-old woman with papillary thyroid cancer underwent 131I therapy after thyroidectomy. Posttherapeutic 131I whole-body scan accidentally showed symmetric “hot spots” in the pelvic region beyond known bone metastases. SPECT/CT was immediately added and revealed metal artifacts with 131I accumulation in the nearby uterus. Further inquiry discovered that she underwent tubal ligation 19 years ago. Our case demonstrates that 131I accumulation can occur at the site of oviducts many years after tubal ligation, which should be distinguished from 131I-avid metastases.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
In this study, we prepared multifunctional microspheres from 131I-labeled hollow copper sulfide nanoparticles loaded with paclitaxel (131I-HCuSNPs-MS-PTX) for imaging and therapeutics of W256/B breast tumors in rats. 18F-fluordeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging detected that the expansion of the tumor volume was delayed (P<0.05) following intra-tumoral (i.t.) injection with 131I-HCuSNPs-MS-PTX plus near-infrared (NIR) irradiation. The immunohistochemical analysis further confirmed the anti-tumor effect. The single photon emission computed tomography (SPECT)/photoacous...
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Conclusions According to our experience, SLNB in males is a reproducible, useful, safe and reliable technique which avoids unnecessary axillary lymphadenectomy and prevents the appearance of undesirable effects.
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Conclusion: Radioembolization with 166Ho-microspheres induced a tumor response with an acceptable toxicity profile in salvage patients with liver metastases.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Clinical Source Type: research
In this study, we evaluated the value of 99mTc-PSMA SPECT/CT radioguided surgery using comparison with histopathological results of dissected specimens.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Prostate Cancer: Localized: Surgical Therapy IV Source Type: research
CONCLUSION: Residual nodal metastasis following initial surgical treatment for regionally advanced differentiated thyroid cancer is rather common on highly sensitive 131-I scans with SPECT/CT and is due to both unrecognized nodal involvement preoperatively and incomplete removal of metastatic lymph nodes during compartment-orientated nodal dissection. The surgical management of high-risk DTC should include preoperative imaging to evaluate for nodal metastases in the central and lateral neck and compartment-orientated nodal dissection of involved compartments. Attention should be given to complete dissection in levels VI, I...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
AbstractPurposeThe gastrin-releasing peptide receptor (GRPR), overexpressed on various tumor types, is an attractive target for receptor-mediated imaging and therapy. Another interesting approach would be the use of GRPR radioligands for pre-operative imaging and subsequent radio-guided surgery, with the goal to improve surgical outcome. GRPR radioligands were successfully implemented in clinical studies, especially Sarabesin 3 (SB3) is an appealing GRPR antagonist with high receptor affinity. Gallium-68 labeled SB3 has goodin vivo stability, after labeling with Indium-111; however, the molecule shows poorin vivo stability...
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research
Authors: Liu C, Gong Q, Chen T, Lv J, Feng Z, Liu P, Deng Z Abstract Multidrug resistance (MDR) is an obstacle for cancer chemotherapy. It was reported that 20(S)-ginsenoside Rg3 (hereafter Rg3) was able to regulate MDR in mouse leukemia cells. The present study investigated the effect of Rg3 on the MDR of A549 lung cancer cells. A cell viability assay revealed that Rg3 treatment increased cisplatin (DDP) cytotoxicity in DDP resistant A549 cells (A549/DDP). Furthermore, Rg3 increases the antitumor effect of DDP on A549/DDP xenograft mice. The expression of MDR-mediated proteins, including P-glycoprotein (P-gp), mul...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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