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Top 10 healthcare 3D printing events of 2016

2016 was an exciting year for 3D printing in healthcare. Big investments, mergers...Read more on AuntMinnie.comRelated Reading: 3D-printed kidneys change preop surgical planning FDA video explains agency's role in 3D printing 4 steps to high-quality 3D printing for radiology 3D-printed kidney phantom advances SPECT/CT calibration 3D-printed models are accurate for complex lung cancers
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Abstract: A 46-year-old man with papillary thyroid cancer post total thyroidectomy was referred for post radioiodine (131I) whole-body scan. Whole-body images revealed intense 131I uptake in the bed thyroid and a focal abnormal uptake in the testicular area. Subsequent SPECT/CT demonstrated that the focal uptake corresponded to the left epididymis, and the pathology report revealed a spermatocele with no immunohistochemical features for thyroid tissue. Many cases of unexpected radioiodine uptake have been reported, and spermatocele could be counted for another possibility of incidental 131I uptake despite an unclear mechanism.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
We report here the three dimensional dose distribution resulting from a NPD incorporating AuNP labeled with electron emitters (<sup>90</sup>Y, <sup>177</sup>Lu, <sup>111</sup>In) of different energies using Monte Carlo based voxel level dosimetry. The MCNP5 dose model was used to assess differences in dose distribution from simulated NPD and conventional brachytherapy sources, positioned in breast tissue simulating material. We further compare these dose distributions in mice bearing subcutaneous human breast cancer xenografts implanted with <sup>177</sup>Lu-AuNP NPD, o...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
AbstractBackgroundImage-based measurement of absorbed dose of Ra-223 dichloride may be useful in predicting therapeutic outcome in patients with castration-resistant prostate cancer (CRPC). In general, SPECT has been found to be more accurate than planar imaging in terms of lesion-based analysis. The aims of this study were to assess the feasibility and clinical usefulness of Ra-223 SPECT.The energy spectrum of Ra-223 and SPECT images of a cylindrical phantom with a hot rod were obtained to determine the collimator candidates and energy window settings suitable for clinical Ra-223 SPECT (basic study A). Another phantom wit...
Source: EJNMMI Research - Category: Radiology Source Type: research
Conclusion: These studies demonstrate that 111In-DTPA-anti-PD-L1 is capable of identifying tumors that overexpresses PD-L1 and monitoring the impact of PD-L1–rich organs on the distribution of anti-PD-L1 antibodies.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Basic Source Type: research
Recent studies have shown enhanced tumor targeting by novel somatostatin receptor (SSTR) antagonists compared with clinically widely used agonists. However, these results have been obtained mostly in neuroendocrine tumors, and only limited data are available for cancer types with lower SSTR expression, including breast cancer (BC). To date, two studies have reported higher binding of the antagonist than the agonist in BC, but in both studies only a limited number of cases were evaluated. In this preclinical study, we further investigated whether the application of an SSTR antagonist can improve SSTR-mediated BC imaging in ...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Basic Source Type: research
Rationale: The spine is the most common site of bone metastases due to thyroid cancer; however, spinal cord compression as a complication of metastatic thyroid cancer is very rare. Patient concerns: A 48-year-old female patient was presented to the Neurosurgical Department, complaining of progressive back neck pain with bilateral upper extremities numbness and weakness for 4 months. Diagnosis: Imaging studies revealed osteolytic destruction in bodies and accessories of the second and third cervical vertebrae with a huge soft-tissue mass compressing spinal cord and causing swelling. After the neurosurgical decompression s...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Cancer Biotherapy&Radiopharmaceuticals Oct 2017, Vol. 32, No. 8: 288-296.
Source: Cancer Biotherapy and Radiopharmaceuticals - Category: Cancer & Oncology Authors: Source Type: research
Conclusion We suggested that the 111In-cetuximab was potential for early diagnosis and prognostic monitor of EGFR-positive CRC in further clinical practice.
Source: Journal of the Chinese Medical Association - Category: General Medicine Source Type: research
Conclusion: MicroSPECT/CT image acquisition and analysis for thyroidal RAI uptake is greatly improved by our cradle and CTViewer software, respectively. Furthermore, our approach of superimposing thyroid VOIs from t24 images to select thyroid VOIs on corresponding aligned t1 images can be applied to studies in which the target tissue has differential radiotracer retention from surrounding tissues. PMID: 28920557 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Publication date: November 2017 Source:Biomedicine & Pharmacotherapy, Volume 95 Author(s): Renata Salgado Fernandes, Carolina de Aguiar Ferreira, Daniel Cristian Ferreira Soares, Anna Margherita Maffione, Danyelle M. Townsend, Domenico Rubello, André Luís Branco de Barros Despite recent advances in the development of new therapeutic agents and diagnostic imaging modalities, cancer is still one of the main causes of death worldwide. A better understanding of the molecular signature of cancer has promoted the development of a new generation of anti-cancer drugs and diagnostic agents that specifically targe...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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