Abbott touts dorsal root ganglion stim study

Abbott (NYSE:ABT) today touted short- and long-term data published in the journal Pain, which demonstrated that its dorsal root ganglion stimulation therapy benefits patients suffering from complex regional pain syndrome more than traditional spinal cord stimulation. The Abbott Park, Ill.-based company said it’s the only company in the world approved to offer DRG stimulation. The newly-published data is from the company’s ACCURATE study, which evaluated DRG stimulation in patients for 3 and 12 months. “Historically, many patients with chronic pain resulting from complex regional pain syndrome or pain resulting from damage to peripheral nerves report inconsistent or inadequate pain relief from tonic spinal cord stimulation. As a physician this is frustrating because our ultimate goal is to deliver options providing meaningful pain relief,” lead author Dr. Timothy Deer said in prepared remarks. “The findings highlighted in our publication align with what I’ve seen in my practice since U.S. approval of DRG stimulation: that DRG stimulation offers a superior option for CRPS-related chronic pain and improved quality of life for my patients.” After 3 and 12 months, patients who received Abbott’s DRG stimulation therapy had meaningful pain relief and 74.2% of them had treatment success, compared to 53% of patients who received traditional SCS. Secondary endpoint data showed that at 12 months, more than a third of the pat...
Source: Mass Device - Category: Medical Equipment Authors: Tags: Clinical Trials Pain Management Research & Development Spinal Abbott Source Type: news

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AbstractObjectiveTo investigate the possible role of serum norepinephrine (NE), leptin and 5 ‐hydroxytryptamine (5‐HT) and their correlations with sympathetic skin response located in the penis (PSSR) in primary premature ejaculation (PPE).MethodsWe compared the serum level of NE, leptin and 5 ‐HT, Intravaginal ejaculatory latency time(IELT) and The Premature Ejaculation Diagnostic Tool (PEDT) scores between 57 PPE patients and 42 healthy control men as controls, who were recruited between September 2016 and January 2019. Additionally, the amplitude and latency of PSSR were measured and compared between the two group...
Source: Andrology - Category: Urology & Nephrology Authors: Tags: ORIGINAL ARTICLE Source Type: research
If you want to be a doctor, hold off on medical school until age 28 - STAT There are advantages to spending your formative years working at a first career and meeting your life partner, and then starting medical school at age 28. "Every generation of physicians must be free to act for itself. Claims to a physician’s 20s have withered away. Corporate health care has deemed physicians replaceable, either by those who accept lower pay or by... STAT: Why Medical School Should Start at 28...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Publication date: Available online 17 February 2020Source: Surgery (Oxford)Author(s): Tristan E. McMillan, Timothy Gardner, Alan J. JohnstoneAbstractTourniquets have been around for many years, providing surgeons with a bloodless operative field and saving lives in the pre-hospital care of major limb trauma. However, their use does come with risk. It is therefore extremely important that we, as surgeons, fully understand the physiological influence they impose on patients, the complications associated with their use and, moreover, how to minimize the incidence of these complications. Most tourniquets are now electronically...
Source: Surgery (Oxford) - Category: Surgery Source Type: research
AbstractBakker et al found a change in the magnetic resonance imaging (MRI) findings in 29 of 188 patients, when the examination was repeated at three months and at one year (1). The patients were all being investigated on account of back pain, with presumably varying degrees of concern about the possibility of inflammatory spondyloarthritis.Twelve (6.8%) patients were negative at the initial examination but became positive on subsequent testing. A percentage that was lower, but not dissimilar to Van Onna et al's report of 15% at two years (2).
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: LETTER TO THE EDITOR Source Type: research
UCLA researchers have found that it is possible to assess a person ’s ability to feel empathy by studying their brain activity while they are resting rather than while they are engaged in specific tasks.  Traditionally, empathy is assessed through the use of questionnaires and psychological assessments. The findings of this study offer an alternative to people who may have difficulty filling out questionnaires, such as people with severe mental illness or autism, said senior author Dr. Marco Iacoboni, professor of psychiatry and biobehavioral sciences at the David Geffen School of Medicine at UCLA.“Assessi...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
In this study, we evaluated the safety, tolerability, and immunogenicity of shorter, simpler regimens of trivalent Ad26.Mos.HIV expressing mosaic HIV-1 Env/Gag/Pol antigens combined with aluminium phosphate-adjuvanted clade C gp140 protein.MethodsWe did this randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) at Beth Israel Deaconess Medical Center in Boston, MA, USA. We included healthy, HIV-uninfected participants (aged 18–50 years) who were considered at low risk for HIV infection and had not received any vaccines in the 14 days before study commencement. We randomly assigned participant...
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
Conditions:   Pain, Postoperative;   Pain, Acute;   Pain, Chronic;   Fractures, Closed;   Fractures, Open Intervention:   Behavioral: Cognitive Behavioural Therapy Sponsors:   McMaster University;   Canadian Institutes of Health Research (CIHR);   Orthopaedic Trauma Association Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Condition:   Chronic Pain Interventions:   Other: Internet-Based Pain Education and Exercise;   Other: Online Booklet Sponsors:   Universidade Cidade de Sao Paulo;   Fundação de Amparo à Pesquisa do Estado de São Paulo Not yet recruiting
Source: - Category: Research Source Type: clinical trials
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Source: - Category: Research Source Type: clinical trials
Condition:   Chronic Pain, Acute Pain, Cotinine, Hysterectomy Intervention:   Device: measuring cotinine level Sponsor:   Mustafa Kemal University Recruiting
Source: - Category: Research Source Type: clinical trials
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