Fetal Alcohol Syndrome a Global Problem: Report

TUESDAY, Jan. 17, 2017 -- About 119,000 children worldwide are born each year with fetal alcohol syndrome (FAS), a new report finds. The syndrome refers to a group of conditions that include poor growth for the baby both in the womb and after...
Source: Drugs.com - Daily MedNews - Category: Journals (General) Source Type: news

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ConclusionsER stress plays an important role in ethanol ‐induced damage to the developing brain. Inhibition of ER stress is neuroprotective and may provide a new therapeutic strategy to treat FASD.This article is protected by copyright. All rights reserved.
Source: Alcoholism: Clinical and Experimental Research - Category: Addiction Authors: Tags: Original Research Article Source Type: research
CONCLUSIONS: ER stress plays an important role in ethanol-induced damage to the developing brain. Inhibition of ER stress is neuroprotective and may provide a new therapeutic strategy to treat FASD. This article is protected by copyright. All rights reserved. PMID: 30403409 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
We present reanalysis and synthesis of results highlighting Wnt transcription factor 7 like 2 (Tcf7l2) gene as uniquely compatible with hippocampal DNA methylation, histone modifications, and gene expression changes in a coordinated response to neurodevelopmental alcohol exposure. We data-mined literature for Tcf7l2 alterations in response to prenatal alcohol exposure. Four studies identified changes in brain Tcf7l2 expression in different FASD models. Further, we performed an in silico TCF7L2 binding site analysis for FASD mouse model datasets. Seven of these published gene lists were significantly enriched for TCF7L2 bin...
Source: Biochemistry and Cell Biology - Category: Biochemistry Authors: Tags: Biochem Cell Biol Source Type: research
Fetal alcohol spectrum disorder (FASD) is a preventable, lifelong neurodevelopmental disorder caused by prenatal alcohol exposure. FASD negatively impacts individual Indigenous communities around the world. Al...
Source: BMC Public Health - Category: Consumer Health News Authors: Tags: Research article Source Type: research
Fetal alcohol spectrum disorder is common and associated with economic costs greater than comparable other childhood and adult disorders. We need to turn our attention to prevention and mitigation.
Source: Journal of Addiction Medicine - Category: Addiction Tags: Commentary Source Type: research
Conclusions: The data on the economic burden of FASD are scarce, and the existing estimates likely underestimate the full economic impact of this disorder on the affected individuals, their caregivers, and society. However, the current research is sufficient to demonstrate that FASD is a serious public health problem associated with tremendous economic burden.
Source: Journal of Addiction Medicine - Category: Addiction Tags: Original Research Source Type: research
Conclusions: Findings indicate that the speech impairment in boys with FASD results from a combination of deficits in multiple subsystems and should be approached as a disorder rather than a developmental delay. The results suggest that reduced speech motor planning/programming, auditory discrimination, and oral motor abilities should be considered in long-term, individually tailored treatment. PMID: 30398563 [PubMed - as supplied by publisher]
Source: American Journal of Speech-Language Pathology - Category: Speech-Language Pathology Authors: Tags: Am J Speech Lang Pathol Source Type: research
Abstract Physical activity (PA) has been demonstrated to have positive effects on cognitive function, particularly executive function (EF) skills. Animal models suggest PA may be effective in ameliorating some of the neuropsychological effects of fetal alcohol spectrum disorder (FASD), but this approach has not been extended to humans. The purpose of this study was to develop a PA program, FAST Club, for children with FASD and to evaluate its effect on a measure of EF. Using a wait-list control design, 30 children age 7-14 yr participated in FAST Club for 2 × 1.5-hr sessions/week for 8 wee...
Source: Adapted Physical Activity Quarterly : APAQ - Category: International Medicine & Public Health Authors: Tags: Adapt Phys Activ Q Source Type: research
From the latestNIAAA Director's Blog:Fetal alcohol spectrum disorders, also known as FASD, is a term that refers to the broad range of lifelong birth defects and neurodevelopmental abnormalities that occur as a result of prenatal alcohol exposure. In this edition of my blog, I want to remind everyone that there is no known safe level of alcohol, or time to drink, during pregnancy.  Read more...
Source: NIAAA News - Category: Addiction Authors: Source Type: news
ConclusionsThe findings highlight an attitude-behavior gap and suggest that positive preventive attitudes are insufficient to elicit FASD preventive behavior. Interventions are needed that go beyond education to build intrinsic motivation and structural support to refrain from alcohol use during pregnancy.
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
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