Maintaining hair follicle stem cell identity in a dish
Identifying and mimicking the signals that regulate stem cell self-renewal, differentiation and maintenance in a petri dish is crucial to faithfully recapitulate stem cell behaviour in vitro. In this issue, Chacón-Martínez et al (2017) describe novel culture conditions that allow the long-term expansion and maintenance of functional murine hair follicle stem cells. This exciting discovery provides a faithful platform to study hair follicle stem cells in vitro and potentially perform drug screening for skin and hair follicle disorders.
Source: EMBO Journal - Category: Molecular Biology Authors: Sanchez-Danes, A., Blanpain, C. Tags: Development & Differentiation, Stem Cells, Systems & Computational Biology News [amp ] Views Source Type: research