Challenges of Decision Making Regarding Futility in a Randomized Trial: The Interventional Management of Stroke III Experience [Clinical Sciences]

Conclusions— Even in spite of prespecified interim analysis boundaries, interim looks at data pose challenges in interpretation and decision making, underscoring the importance of objective stopping criteria. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.

http://stroke.ahajournals.org/cgi/content/short/45/5/1408?rss=1

Source: Stroke - April 28, 2014 Category: Neurology Authors: Yeatts, S. D., Martin, R. H., Coffey, C. S., Lyden, P. D., Foster, L. D., Woolson, R. F., Broderick, J. P., Di Tullio, M. R., Jungreis, C. A., Palesch, Y. Y., for the IMS III Investigators Tags: Emergency treatment of Stroke Clinical Sciences Source Type: research