Estimate of false-positive breast cancer diagnoses from accuracy studies: a systematic review.

CONCLUSIONS: High heterogeneity of the included studies precluded formal pooling estimates. When considering studies of higher sample size or methodological quality, false-positive rates and MBM are around 1%. The impact of false-positive histological diagnoses of breast cancer on unnecessary treatment, as well as that of overdiagnosis, is not negligible and is of importance in clinical practice.
PMID: 28073996 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - January 9, 2017 Category: Cancer & Oncology Authors: Segnan N, Minozzi S, Ponti A, Bellisario C, Balduzzi S, González-Lorenzo M, Gianola S, Armaroli P Tags: J Clin Pathol Source Type: research