Twist and turn into chronic disorders of  consciousness: Potential role of the auditory stapedial reflex.

CONCLUSION: We hypothesize that our conditioning protocol may have entrained and potentiated some spared cortico-subcortical networks that sustained the clinical and electrophysiological amelioration we found. Our data electrophysiologically demonstrate for the first time that primary the auditory area can influence ASR elicitation, and such finding may support the DOC differential diagnosis. PMID: 28059800 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

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CONCLUSIONS: While both sound types had a positive impact on many dimensions of tinnitus, only the broadband noise was associated with a reduction in blood pressure. These results are consistent with a complex interaction between sound and tinnitus and suggest a multifactorial basis to sound therapy that includes a reduction in arousal. PMID: 31519289 [PubMed - in process]
Source: Complementary Therapies in Medicine - Category: Complementary Medicine Authors: Tags: Complement Ther Med Source Type: research
This study investigated changes in sleep architecture during ASV treatment in HFrEF patients.MethodsA retrospective analysis of polysomnographic datasets for 30 ASV-treated patients with stable HFrEF and moderate-to-severe CSA was performed, including blinded analyses of total sleep time (TST), and percentage of REM and non-REM sleep (stages N1-N3).ResultsFollow-up was 109 ± 32 days; mean device usage was 6.0 ± 1.1 h/day. During ASV there was reduction of N1 (34 ± 20%/TST to 13 ± 5%/TST, p 
Source: Respiratory Physiology and Neurobiology - Category: Respiratory Medicine Source Type: research
This study aimed to determine the role of the endocardial endothelium (EE) in the cardiac β-adrenergic (β-AR) remodeling at the early phase of endotoxemic shock.Main methodsRats received either lipopolysaccharide (LPS) or saline (control) intravenously. Three hours later, β-AR cardiac contractility was evaluated on papillary muscles with or without a functional EE.Key findingsIsoproterenol-induced contractility was strongly increased in papillary muscles from LPS rats. A similar increase was observed with a β1-AR stimulation, whereas β2-AR and β3-AR produced similar contractility in control an...
Source: Life Sciences - Category: Biology Source Type: research
Authors: Suwal B, Bajimaya S, Bernstein PS PMID: 31512983 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
ConclusionsOur results suggest that burn patients have a sensitivity dysfunction in postburned skin areas. The use of QST could be considered the technique to determine the sensitivity of burned patients. Although, more high-quality studies should to be done.
Source: Burns - Category: Dermatology Source Type: research
Publication date: Available online 13 September 2019Source: International OrthodonticsAuthor(s): Yingzhi Gu, Rui Zhuang, Xianju Xie, Dongliang Zhang, Yuxing BaiSummaryObjectiveElectric resistance heat treatment procedures are performed by most orthodontists; however, the effects of electrothermal treatment on the mechanical properties, surface morphology, phase transition, colour and arch width of stainless steel archwires remain controversial and are worthy of investigation.Materials and methodsStainless steel archwires (0.017 × 0.025 and 0.019 × 0.025 inches) were heat-treated using a spot...
Source: International Orthodontics - Category: Dentistry Source Type: research
Publication date: Available online 13 September 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): Anu Kansal, John HughesAbstractPain is one of the most common symptoms that patient presents with. Visceral organs were thought to be insensitive to pain in the past, but we now know this is not true. It is more common than somatic pain and originates from the internal organs in the thorax, abdomen or pelvis. These organs are innervated by the parasympathetic (vagus and sacral parasympathetic fibres) and sympathetic (thoracolumbar sympathetic chain: T1–L2) nervous systems. The afferent and efferent fibres to...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Authors: Sato H, Mizuno KI, Hashimoto S, Takatsuna M, Terai S Abstract Myotonic dystrophy is a progressive disorder mainly affecting the voluntary muscles. We herein report a rare case of myotonic dystrophy complicated with high-resolution manometry-defined achalasia, the pathology of which is absent relaxation of the smooth muscles of lower esophageal sphincter (LES). In the present case, achalasia was considered a complication of myotonic dystrophy instead of sporadic achalasia, as on performing high-resolution manometry, the finding of an impaired LES relaxation (myotonic phase) changed to a totally emaciated LE...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
William Withering the British Botanist of 18th century now laid to rest in the St Barthomlew Churchyard ,Edgbaston is known for his astonishing isolation of the wonder moelcule Digoxin from Foxglove. (Of course, let us not forget original old lady Ms. Hutton from Shropshire who was treating epidemic dropsy with a concoction of herbal Tea ) He reported this in the seminal paper “An account of Foxglove’ in the year 1750 and subsequently became a fellow of Royal college of science. (The story of Withering and Digoxin is extensively researched and written by Dr Dennis M, Krikler in a classic review article of 198...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: cardiac failure history of cardiology dig trial radiance proved history of digoxin Source Type: blogs
CONCLUSION: Autonomic functions should be questioned in detail as well as motor and sensory symptoms of RLS, and care should be taken especially on cardiac dysfunction. PMID: 31520300 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - Category: Sleep Medicine Authors: Tags: Sleep Breath Source Type: research
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