Appropriate timing to start and optimal response evaluation of high-dose corticosteroid therapy for patients with acute liver failure

ConclusionsWe propose the appropriate timing to start high-dose corticosteroid therapy in patients with ALI/ALF; 40% of JHEPM probability, 1.53 of PT-INR, and 52% of PT because these values were theoretically discriminated at 98% coverage to the patients with coma. Because the study contained selection bias, the appropriate timing for therapy should be confirmed in a future prospective study.

http://link.springer.com/10.1007/s00535-017-1306-5

Source: Journal of Gastroenterology - January 10, 2017 Category: Gastroenterology Source Type: research