MicroRNA expression shows inflammatory dysregulation and tumor ‐like proliferative responses in joints of patients with post‐infectious Lyme arthritis

Conclusions: During active infection, microRNA expression in SF reflected an immune response associated with bacterial killing, whereas in post‐infectious LA, microRNA expression in SF and synovial tissue reflected chronic inflammation, synovial proliferation, and breakdown of wound repair processes, showing that the nature of the arthritis was altered after spirochetal killing. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - Category: Rheumatology Authors: Tags: Full Length Source Type: research