Anthracycline-based induction chemotherapy followed by concurrent cyclophosphamide, methotrexate and 5-fluorouracil and radiation therapy in surgically resected axillary node-positive breast cancer.

In conclusion, induction AT concurrent CMF and XRT and dose-dense chemotherapy followed by AI in N+ high-risk breast cancer was associated with a low level of systemic and late cardiac toxicity and excellent local control, DFS and OS.
PMID: 24772320 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - May 1, 2014 Category: Cancer & Oncology Authors: Recchia F, Candeloro G, Cesta A, DI Staso M, Bonfili P, Gravina GL, DI Cesare E, Necozione S, Rea S Tags: Mol Clin Oncol Source Type: research