Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1+ monocytes
Conclusions
Ang-1 specifically increases circulating Gr1+ inflammatory monocytes and increases monocyte/macrophage retention in atherosclerotic plaques, thereby contributing to development of atherosclerosis.
Source: Cardiovascular Research - Category: Cardiology Authors: Fujisawa, T., Wang, K., Niu, X.-L., Egginton, S., Ahmad, S., Hewett, P., Kontos, C. D., Ahmed, A. Tags: Vascular biology Source Type: research