Common therapeutic modalities against diabetes and associated cardiovascular disease.

Common therapeutic modalities against diabetes and associated cardiovascular disease. Curr Vasc Pharmacol. 2017 Jan 05; Authors: Jabir NR, Firoz CK, Ashraf GM, Zaidi SK, Shakil S, Kamal MA, Tabrez S Abstract Despite recent advances in medical research, the incidence of diabetes and cardiovascular disease (CVD)-induced fatal events is increasing. The literature point towards several co-occurring pathways that could lead to terminal complications related with these diseases. Different pathophysiological alterations such as hyperglycaemia, hyperinsulinaemia, insulin resistance, obesity, endothelial dysfunction and oxidative stress lead to the initiation and progression of atherosclerotic plaques. In view of the continuous rise in fatal events and overlapping pathological conditions associated with CVD and diabetes, there is a critical need to develop a common treatments against these diseases. The present review highlights the possible use of common drugs that could target diabetes and associated CVD. PMID: 28056755 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research

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