Common therapeutic modalities against diabetes and associated cardiovascular disease.
Common therapeutic modalities against diabetes and associated cardiovascular disease. Curr Vasc Pharmacol. 2017 Jan 05; Authors: Jabir NR, Firoz CK, Ashraf GM, Zaidi SK, Shakil S, Kamal MA, Tabrez S Abstract Despite recent advances in medical research, the incidence of diabetes and cardiovascular disease (CVD)-induced fatal events is increasing. The literature point towards several co-occurring pathways that could lead to terminal complications related with these diseases. Different pathophysiological alterations such as hyperglycaemia, hyperinsulinaemia, insulin resistance, obesity, endothelial dysfunction and oxidative stress lead to the initiation and progression of atherosclerotic plaques. In view of the continuous rise in fatal events and overlapping pathological conditions associated with CVD and diabetes, there is a critical need to develop a common treatments against these diseases. The present review highlights the possible use of common drugs that could target diabetes and associated CVD. PMID: 28056755 [PubMed - as supplied by publisher]
Date: Monday, 11 25, 2019; Speaker: Doug Chang, Thirst and water intake responses in obese and normal weight men, The Bogardus group, PECRB, NIDDK; Cuiying Xiao, Contribution of BRS3 in MC4R/SIM1 neurons to body weight/termperature in mice, The Reitman group, DEOB, NIDDK; Building: Building 10 (Clinical Center); Solarium Conference Room 9S233 (old Bunim Room)
"We believe that one of the drivers of the obesity epidemic is ready access to energy dense, hyperpalatable foods," says an expert. Having a standard, universal definition is therefore key.Medscape Medical News
Conclusion: The epidemiological issues of MetS in Beijing adolescents should be known across socioeconomic classes. Early intervention strategies, such as dietary pattern interventions and physical excise, should be designed for that population to reduce the disease burdens of cardiovascular disease (CVD), Type 2 diabetes (T2D), and steatohepatitis in adulthood.
AbstractLongitudinal and observational studies have found a link between the consumption of sugar-sweetened beverages (SSBs) and non-communicable diseases (NCDs) including obesity and diabetes. Following World Health Organization (WHO) recommendations, SSB taxes have been implemented in over 40 countries and cities to reduce sugar consumption. Despite continuing battles with communicable diseases in low- and middle-income countries (LMICs), an epidemiological transition towards NCDs warrants SSB tax implementation. However, LMICs face challenges when implementing SSB taxes including a lack of resources and opposing argumen...
The number of people who are obese in England has almost doubled in the last 20 years, according to new analysis from Diabetes UK.
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
TYPE 2 diabetes accounts for 90 percent of all diabetes cases and is linked with obesity. The condition has been growing at a particularly high rate and is now one of the world ’s most common long term health conditions. Eating this delicious fruit could help keep blood sugar levels low. What is it?
ConclusionsTaken together, these results illustrate a new model in which Purβ functions to regulate the glucagon/ADCY6/cAMP/PKA/CREB signaling pathway to help maintain glucose homeostasis.Graphical abstract