The thyroid, the eyes and the gut: a possible connection

ConclusionIn this scenario, a Marie Sklodowska –Curie funded project INDIGO (http://www.indigo-iapp.eu/) is investigating the role of the gut bacteria in GD and GO pathogenesis. The gut is the first and the widest area of bacteria access, with the highest concentration of T cells in the human body and trained to react to microorganisms. Interestingly, all the environmental factors involved in GD and GO pathogenesis can alter the balance within the microorganisms located in the gut, and influence the immune system, in particular the proportions of regulatory Treg and inflammatory TH17 cells. It is hoped that investigating GD and GO pathogenesis from this novel aspect will identify new targets for prevention and treatment.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research