Three new flavonoid glycosides from the aerial parts of Graptophyllum grandulosum Turril (Acanthaceae)

Publication date: March 2017 Source:Phytochemistry Letters, Volume 19 Author(s): Cyrille Ngoufack Tagousop, David Ngnokam, Dominique Harakat, Laurence Voutquenne-Nazabadioko Grandulosides A-C, three new flavonoid glycosides, were isolated from the aerial parts of Graptophyllum grandulosum Turill and identified as chrysoeriol-7-O-β-d-apiofuranosyl-(1→2)-β-d-xylopyranoside (1), chrysoeriol-7-O-[4′′′-O-acetyl-β-d-apiofuranosyl-(1→2)]-β-d-xylopyranoside (2) and 7-O-α-l-rhamnopyranosyl-(1→6)-β-d-(4′′-Sodium hydrogeno sulfate) glucopyranoside (3). Four known compounds, chrysoeriol-7-O-β-d-xyloside (4), isorhamnetin-3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside (5), luteolin-7-O-β-d-apiofuranosyl-(1→2)-β-d-xylopyranoside (6) and sucrose (7) were also obtained. The structures of these compounds were established by interpretation of their spectral data, mainly HR-TOFESIMS, 1D-NMR (1H, 13C) and 2D-NMR (COSY, NOESY, HSQC and HMBC) and by comparison with the literature data. Graphical abstract

Source: Phytochemistry Letters - January 5, 2017 Category: Chemistry Source Type: research