Simultaneously-evoked Auditory Potentials (SEAP): a new method for concurrent measurement of cortical and subcortical auditory-evoked activity.
Simultaneously-evoked Auditory Potentials (SEAP): a new method for concurrent measurement of cortical and subcortical auditory-evoked activity.
Hear Res. 2016 Dec 30;:
Authors: Slugocki C, Bosnyak D, Trainor LJ
Abstract
Recent electrophysiological work has evinced a capacity for plasticity in subcortical auditory nuclei in human listeners. Similar plastic effects have been measured in cortically-generated auditory potentials but it is unclear how the two interact. Here we present Simultaneously-Evoked Auditory Potentials (SEAP), a method designed to concurrently elicit electrophysiological brain potentials from inferior colliculus, thalamus, and primary and secondary auditory cortices. Twenty-six normal-hearing adult subjects (mean 19.26 years, 9 male) were exposed to 2400 monaural (right-ear) presentations of a specially-designed stimulus which consisted of a pure-tone carrier (500 or 600 Hz) that had been amplitude-modulated at the sum of 37 and 81 Hz (depth 100%). Presentation followed an oddball paradigm wherein the pure-tone carrier was set to 500 Hz for 85% of presentations and pseudo-randomly changed to 600 Hz for the remaining 15% of presentations. Single-channel electroencephalographic data were recorded from each subject using a vertical montage referenced to the right earlobe. We show that SEAP elicits a 500 Hz frequency-following response (FFR; generated in inferior colliculus), 80 (subcortical) and 40 (primary auditory c...
Source: Hearing Research - Category: Audiology Authors: Slugocki C, Bosnyak D, Trainor LJ Tags: Hear Res Source Type: research