Early Clinical Response as a Predictor of Late Treatment Success in Patients With Acute Bacterial Skin and Skin Structure Infections: Retrospective Analysis of 2 Randomized Controlled Trials
In the treatment of acute bacterial skin and skin structure infections, pooled data from 2 clinical trials (N = 1333 patients) showed that programmatic and investigator-assessed early treatment success both had a high positive predictive value (94.3%–100.0%) for late clinical cure, including among hospitalized patients. The negative predictive value of programmatic early success was <20%. These exploratory findings require prospective real-world evaluation.
Clinical Trials Registration. NCT01170221; NCT01421511.
Source: Clinical Infectious Diseases - Category: Infectious Diseases Authors: Nathwani, D., Corey, R., Das, A. F., Sandison, T., De Anda, C., Prokocimer, P. Tags: Brief Report Source Type: research