Fixed-Dose Artesunate-Amodiaquine Combination vs Chloroquine for Treatment of Uncomplicated Blood Stage P. vivax Infection in the Brazilian Amazon: An Open-Label Randomized, Controlled Trial

Conclusions.
ASAQ exhibited high efficacy against CQ resistant P. vivax and is an adequate alternative in the study area. Studies with an efficacious comparator, longer follow-up and genotype-adjustment can improve CQR characterization.
Clinical Trials Registration. NCT01378286.

Source: Clinical Infectious Diseases - January 3, 2017 Category: Infectious Diseases Authors: Siqueira, A. M., Alencar, A. C., Melo, G. C., Magalhaes, B. L., Machado, K., Alencar Filho, A. C., Kuehn, A., Marques, M. M., Manso, M. C., Felger, I., Vieira, J. L. F., Lameyre, V., Daniel-Ribeiro, C. T., Lacerda, M. V. G. Tags: Major Article Source Type: research