CorMatrix valved conduit in a porcine model: long-term remodelling and biomechanical characterization

CONCLUSIONS
CorMatrix is biodegradable; however, it failed to remodel in a structured and anatomical fashion in an arterial environment. Progressive mechanical and remodelling failure in this scenario might be explained by the complexity of the conduit design and the host's chronic inflammatory response, leading to early fibrosis and calcification.

Source: Interactive CardioVascular and Thoracic Surgery - January 3, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Mosala Nezhad, Z., Poncelet, A., de Kerchove, L., Fervaille, C., Banse, X., Bollen, X., Dehoux, J.-P., El Khoury, G., Gianello, P. Tags: History ADULT CARDIAC Source Type: research