Pre-operative Radiation Therapy with Surgery

Currently, no consensus has yet been reached regarding the best treatment of resectable malignant pleural mesothelioma (MPM) (1). The importance of a macroscopically complete resection, given the poor clinical outcomes seen in some MPM studies of patients undergoing extrapleural pneumonectomy (EPP) (2), is controversial. The treatment options include the best supportive care, palliative chemotherapy/RT, and multimodal therapy with curative intent. In our institution, we are conducting the SMART (Surgery for Mesothelioma After RT) study, in which patients with resectable MPM receive neoadjuvant accelerated hemithoracic RT and EPP the following week.

http://www.redjournal.org/article/S0360-3016(16)33134-0/fulltext?rss=yes

Source: International Journal of Radiation Oncology * Biology * Physics - January 4, 2017 Category: Radiology Authors: B.C. John Cho Tags: Feature Source Type: research