Solving the Mystery Flu That Killed 50 Million People

MoreCalifornia Bill Banning ‘Affluenza’ Defense Is Nixed7 Ebola Patients in Guinea Fight Off the Disease4 Diseases Making a Comeback Thanks to Anti-VaxxersYears ago the environmental historian Alfred Crosby was at Washington State University, where he was teaching at the time, when on a whim he decided to pick up an old almanac from 1917. (This is apparently the kind of thing historians like to do in their spare time.) He looked up the U.S. life expectancy in that year—it was about 51 years. He turned to the 1919 almanac, and found about the same figure. Then Crosby picked up the almanac from 1918. The U.S. life expectancy in 1918 had fallen to 39 years. “What the hell happened?” Crosby told the New York Times writer Gina Kolata in her book Flu: The Story of the Great Influenza Pandemic of 1918. “ The life expectancy had dropped to what it had been fifty years before.” MoreMumps Outbreak Reported at University of IllinoisAlmost Half of Homeless Men Had a Previous Brain InjuryMen Charged With Toppling Ancient Rock Formation Avoid Jail Time Huffington PostHere's An Updated Tally Of All The People Who Have Ever Died From A Marijuana Overdose Huffington PostTony Awards 2014: Neil Patrick Harris, Bryan Cranston, Chris O'Dowd Score Nods PeopleWhat happened was the 1918 influenza pandemic. A virus that usually does little more than make people feel awful for a few days killed an estimated 50 million people worldwide, if not far more, with 65...
Source: TIME: Top Science and Health Stories - Category: Science Authors: Tags: Uncategorized 1918 pandemic avian flu bird flu death rates H1N1 H5N1 H7N9 health immune system influenza Spanish flu Source Type: news

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Authors: Figoni J, Chirouze C, Hansmann Y, Lemogne C, Hentgen V, Saunier A, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Caumes E, Eldin C, de Broucker T, Jaulhac B, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Gocko X, Dieudonné M, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Lenormand C, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P, endorsed by scientific societies Abstract Lyme borreliosis is transmitted en France by the tick Ixodes ricinus, endemic in metropolitan France. In the absence of vaccine licensed for use in humans, primary prevent...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
ConclusionsThis Phase I trial showed the MDCK-derived H5N1 candidate vaccine is safe and immunogenic. The source of RBCs has a significant impact on the measurement of HAI titers ( number: NCT01675284.).
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
ConclusionsHand hygiene and an intensive isolation strategy remained the most critical precautions for preventing an outbreak of healthcare-associated viral gastroenteritis in the neonate care unit.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
In this study we have generated several non-conform vaccine lots by an excessive inactivation with β-propiolactone (BPL) and assessed the capacity of both tests to detect the corresponding consequences. Excessive BPL inactivation causes G-protein unfolding, altering in turn viral morphology and the continuity of the G-protein layer in the viral particle. Both the NIH and the ELISA tests were able to monitor the consequences of excessive inactivation in a similar manner. Of note, the experimental error of the ELISA test was well below that of the NIH test. These results increase the prospect that the ELISA test could b...
Source: Biologicals - Category: Biology Source Type: research
CONCLUSION: ANE is a distinctive type of acute encephalopathy with diverse clinical spectrum. Even though the diagnostic criteria are available, they might not be watertight. In addition, treatment options are still limited. Further studies for better outcome are needed. PMID: 31099193 [PubMed - in process]
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research
Publication date: Available online 17 May 2019Source: Preventive MedicineAuthor(s): Jessica L. Gleason, Amelia Jamison, Vicki S. Freimuth, Sandra Crouse QuinnAbstractRacial disparities in influenza vaccination persist between African American and White adults. It is critical to explore the reasons behind this disparity, which may be linked to the use of “folk” or home remedies for illness prevention and treatment. For this study, The GfK Group was contracted to conduct a nationally-representative survey (n = 819 African American and 838 White respondents). Respondents were asked about behaviors, attitudes, ...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
During radiotherapy (RT) treatment, variations such as patient weight loss, tumor regression and diminution of the volume of organs at risk (OARs) may occur. These discrepancies may result in changes in the dose distribution with a risk of overdose to the OARs which cannot be compensated for by a simple rigid repositioning. In order to more easily prioritize these variations according to their potential impact, an image-guided Traffic Light Protocol (IG-TLP) has been put into practice as a decision support system (DSS).
Source: Journal of Medical Imaging and Radiation Sciences - Category: Radiology Authors: Source Type: research
CONCLUSIONS: Tregs and Th cells did not affect OMP-specific immunoglobulin A production in this study. However, these cells may partially inhibit B-cell functions, such as T-cell activation. These inhibitory effects may be related to interleukin-10. PMID: 31092026 [PubMed - in process]
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
[This Day] Maiduguri -M édecines Sans Frontières (MSF), popularly known as Doctors Without Borders on Friday revealed that 58 people had been killed by measles in Borno State since January.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
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