Seizures in the Preterm Neonate

Preterm infants are at high risk for central nervous system injury, with seizures occurring in 6% to 48% of this population. Seizures are more likely to contribute to adverse neurodevelopmental outcomes in preterm infants. Preterm infants are also more likely to have subclinical seizures; therefore, electrographic detection is essential for their diagnosis. Once identified, seizures are traditionally treated with phenobarbital, but newer-generation antiepileptic medications have growing evidence for safety and efficacy. The treatment of seizures may also affect neurodevelopmental outcome.
Source: NeoReviews recent issues - Category: Pediatrics Authors: Tags: Pediatric Drug Labeling Update Articles Source Type: news