Low Level of Blood CD4+ T Cells Is an Independent Predictor of Inferior Progression-free Survival in Diffuse Large B-cell Lymphoma

Immune cell subsets in the blood of patients with diffuse large B-cell lymphoma before therapy were characterized by flow cytometry, and the levels of various T-cell types and natural killer cells were correlated with the eventual outcomes. High absolute levels of CD4 cells in the blood correlated with better progression-free survival and, to a lesser extent, overall survival, independent of patient age and International Prognostic Index score.

Source: Clinical Lymphoma, Myeloma and Leukemia - November 28, 2016 Category: Hematology Authors: Julia Judd, Essel Dulaimi, Tianyu Li, Michael M. Millenson, Hossein Borghaei, Mitchell R. Smith, Tahseen Al-Saleem Tags: Original Study Source Type: research