Menactra (Polysaccharide Diphtheria Toxoid Conjugate Vaccine) - updated on RxList

Source: RxList - New and Updated Drug Monographs - Category: Drugs & Pharmacology Source Type: news

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Source: Clinical and Experimental Immunology - Category: Allergy & Immunology Authors: Tags: Original Article Source Type: research
Many commentators have recentlywritten andsaid that members of the migrant caravan and Central American immigrants in general are diseased.   Former Immigration and Customs Enforcement agent David Ward claimed that the migrants are “coming in with diseases such as smallpox,” a disease that the World Health Organization (WHO) certified as beingeradicated in 1980.   One hopes Mr. Ward was more careful in enforcing American immigration law than in spreading rumors that migrants are carrying one of the deadliest diseases in human history nearly 40 years after it was eradicated from the human population.&n...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
THURSDAY, Nov. 1, 2018 -- Tetanus, diphtheria, and acellular pertussis (Tdap) vaccines given to pregnant women early in the third trimester may offer the most protection against infant pertussis, according to a study published in the Oct. 9 issue of...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
Abstract A follow-up serological study was conducted involving 47 subjects who received four doses of diphtheria and tetanus toxoids combined with acellular pertussis vaccine (DTaP) together with Salk-type inactivated polio vaccine (DTaP-wIPV) until 6 years of age. All antibody levels declined more rapidly than expected within 3 years after the completion of the primary vaccination with 4th booster dose and titers persisted until 6 years of age. The positive rate of the IgG antibody against pertussis toxin (PT) was 31.9% (15/47) at 4 years of age, 41.0% (16/39) at 5 years of age, and 40.5% (15/37) at 6 years of ag...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research
Conclusion The Sphere Handbook was conceived in 1997 by a group of non-governmental organisations, in part to respond to the overall lack of accountability experienced during, and in the aftermath of, the Rwandan genocide in 1994. The Sphere Project developed from a recognition amongst humanitarian actors of the need for greater accountability and effectiveness in humanitarian response. Twenty years later, these concepts that underpin the Sphere Handbook remain as relevant as ever, in a time when humanitarian actors require up-to-date guidance to assist in their response to established and emerging issues, such as the mana...
Source: PLOS Currents Disasters - Category: International Medicine & Public Health Authors: Source Type: research
Authors: Rengganis I Abstract Low adult vaccination coverage in Indonesia may contribute to a recent outbreak of diphtheria in Indonesia. Although well known as a pediatric vaccine, diphtheria vaccination should be administered as booster to adolescence and adults for longer prevention. Adult vaccine differs from pediatric vaccine but have similar protection. Additionally, there is special recommendation to vaccinate pregnant women and elderly people aged 65 years or more. PMID: 30333279 [PubMed - in process]
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research
In this study, to develop a sandwich ELISA that can detect CRM₁₉₇ and CRM₁₉₇ conjugate vaccines, we generated a human anti-CRM₁₉₇ monoclonal antibody (mAb) 3F9 using a phage-displayed human synthetic Fab library and produced mouse anti-CRM₁₉₇ polyclonal antibody. The affinity (KD) of 3F9 for CRM197 was 3.55 nM, based on Bio-Layer interferometry, and it bound specifically to the B fragment of CRM197. The sandwich ELISA was carried out using 3F9 as a capture antibody and the mouse polyclonal antibody as a detection antibody. The detection limit of the sandwich ELISA was
Source: Journal of Microbiology and Biotechnology - Category: Biotechnology Authors: Tags: J Microbiol Biotechnol Source Type: research
This report summarizes vaccination coverage and exemption estimates collected by state and local immunization programs* for children in kindergarten (kindergartners) in 49 states and the District of Columbia (DC) and kindergartners provisionally enrolled (attending school without complete vaccination or exemption while completing a catch-up vaccination schedule) or in a grace period (a set interval during which a student may be enrolled and attend school without proof of complete vaccination or exemption) for 28 states. Median vaccination coverage† was 95.1% for the state-required number of doses of diphtheria and t...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
We report the results of the 2007 national serological survey of immunity to diphtheria in Australia to assess the impact of recent schedule changes on diphtheria immunity, and the adequacy of current policy in the context of increased international travel of people and pathogens. Residual sera (n =1656) collected opportunistically from Australian laboratories in 2007 were tested for diphtheria antibody levels using an enzyme immunoassay, with the protective threshold defined as ≥0.1 IU/mL. About 40% of adults aged ≥30 years are susceptible to diphtheria; following the removal of the 18 month booster and its replacem...
Source: Infectious Disorders Drug Targets - Category: Infectious Diseases Authors: Tags: Infect Disord Drug Targets Source Type: research
This prospective cohort study assesses whether maternal immunization with tetanus, diphtheria, and acellular pertussis (Tdap) vaccine, compared with no immunization, is associated with high concentrations of pertussis toxin antibodies at birth and if there is an optimal gestational age for maternal immunization.
Source: JAMA - Category: General Medicine Source Type: research
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