Recoverable nanocatalyst for the preparation of 2-amino-5,10-dihydro-5,10-dioxo-4H-benzo[g]chromenes and tetrahydrobenzo[g]quinoline-5,10-diones.

Recoverable nanocatalyst for the preparation of 2-amino-5,10-dihydro-5,10-dioxo-4H-benzo[g]chromenes and tetrahydrobenzo[g]quinoline-5,10-diones. Comb Chem High Throughput Screen. 2016 Dec 23; Authors: Ghasemzadeh MA, Elyasi Z, Azimi-Nasrabad M, Mirhosseini-Eshkevari B Abstract In this research an advanced and effective approach for the three-component reactions of malononitrile, 2-hydroxynaphthalene-1,4-dione and diverse aromatic aldehydes has been described using amino-functionalized Fe3O4@SiO2 as catalyst under reflux conditions. In addition, Fe3O4@SiO2-NH2 nanocomposite catalyzed four-component synthesis of tetrahydrobenzo[g]quinolines. The structure of nanocatalyst was determined by FT-IR, SEM, XRD, EDX and VSM analysis. The remarkable advantages of the presented method are environmentally friendly, low cost, excellent yields and absent of hazardous and toxic catalysts. PMID: 28017132 [PubMed - as supplied by publisher]
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Tags: Comb Chem High Throughput Screen Source Type: research