CXCL12 mediates glioblastoma resistance to radiotherapy in the subventricular zone

Conclusion.
Together, these data provide evidence on how the adult SVZ environment, through the release of CXCL12, supports GBM therapeutic failure and potential tumor relapse.

Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Authors: Goffart, N., Lombard, A., Lallemand, F., Kroonen, J., Nassen, J., Di Valentin, E., Berendsen, S., Dedobbeleer, M., Willems, E., Robe, P., Bours, V., Martin, D., Martinive, P., Maquet, P., Rogister, B. Tags: Basic and Translational Investigations Source Type: research