Manuscript title: Acute Effects of Aceclofenac, COX-2 inhibitor, on Penicillin-Induced Epileptiform Activity.

CONCLUSION: The results indicated that not all of the COX-2 inhibitors may have anticonvulsant or proconvulsant features on patients with epilepsy susceptibility and must be used with great care. It was also suggested that not only cyclooxygenase metabolic pathway but also lipoxygenase pathway should be considered together in further detailed studies. PMID: 28017780 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - Category: Neurology Authors: Tags: Brain Res Bull Source Type: research