Prognostic Implications of Monosomies in Patients with Multiple Myeloma

Conclusion In addition to known cytogenetic abnormalities, such as monosomy 13, hypodiploidy and TP53 (17p) deletion, monosomy 16, and loss of the Y chromosome have adverse prognostic implications in patients with MM. Teaser This study evaluated the prevalence and prognostic implications of monosomies in 170 Korean patients with multiple myeloma (MM). Monosomies in chromosomes 16, chromosomes 13, TP53 (17p) deletion, and hypodiploidy had adverse prognostic implications in patients with MM.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research