TWiV 421: Like flies on shot

Hosts:  Vincent Racaniello,  Dickson Despommier,  Alan Dove,  Rich Condit, and  Kathy SpindlerGuest:  Nathan LettsThe TWiVnauts present another example of an infectious but replication incompetent  vaccine, an insect specific arborvirus bearing chikungunya virus structural proteins. Become a  patron of TWiV!Links for this episodeRegister for ASV 2017ASM-ASV  Conference on  Interplay of Viral and Bacterial PathogensChikungunya virus vaccine using insect virus platform (Nat Med)Ebola vaccine results (NYTimes,  paper)Letters read on TWiV 421This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non ­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.Weekly Science PicksAlan - Open Access ButtonDickson - National Geographic PhotographsKathy - World's Tiniest Radio ReceiverNathan - Mutter Museum, PhiladelphiaVincent - How Rogue One is Connected to the MacListener PickSam - Cell Lab: Evolution SandboxHannelore - Congressional DishJohnye - The Fungi in Your FutureBrendan - Zimmer on Longform podcastSend your virology questions and comments t...
Source: This Week in Virology - MP3 Edition - Category: Virology Authors: Source Type: podcasts

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, Norheim G Abstract Today's world is characterized by increasing population density, human mobility, urbanization, and climate and ecological change. This global dynamic has various effects, including the increased appearance of emerging infectious diseases (EIDs), which pose a growing threat to global health security.Outbreaks of EIDs, like the 2013-2016 Ebola outbreak in West Africa or the current Ebola outbreak in Democratic Republic of the Congo (DRC), have not only put populations in low- and middle-income countries (LMIC) at risk in terms of morbidity and mortality, but they also have had a significant impa...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - Category: International Medicine & Public Health Authors: Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research
Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Jacobs Robin Ketteler Marcus Dorner Mark Marsh Viruses are a major threat to human health and economic well-being. In recent years Ebola, Zika, influenza, and chikungunya virus epidemics have raised awareness that infections can spread rapidly before vaccines or specific antagonists can be made available. Broad-spectrum antivirals are drugs with the potential to inhibit infection by viruses from different groups or families, which may be deployed during outbreaks when specific diagnostics, vaccines or directly acting antivirals are not available. While pathogen-directed approaches are generally effective against ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
This report summarizes the lectures held at the meeting and highlights advances in the field.
Source: Antiviral Therapy - Category: Virology Source Type: research
This report summarizes the lectures held at the meeting and highlights advances in the field. PMID: 30597184 [PubMed - as supplied by publisher]
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
Publication date: Available online 17 March 2018Source: Microbes and InfectionAuthor(s): Sagar B. Kudchodkar, Hyeree Choi, Emma L. Reuschel, Rianne Esquivel, Jackie Jin-Ah Kwon, Moonsup Jeong, Joel N. Maslow, Charles C. Reed, Scott White, J. Joseph Kim, Gary P. Kobinger, Pablo Tebas, David B. Weiner, Kar MuthumaniAbstractVaccines are considered one of the greatest advances in modern medicine. The global burden of numerous infectious diseases has been significantly reduced, and in some cases, effectively eradicated through the deployment of specific vaccines. However, efforts to develop effective new vaccines against infect...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
DAVID E. BLOOM is the Clarence James Gamble Professor of Economics and Demography, DANIEL CADARETTE is a research assistant, and JP SEVILLA is a research associate, all at Harvard University’s T.H. Chan School of Public Health.By David E. Bloom, Daniel Cadarette and JP SevillaWASHINGTON DC, Jul 3 2018 (IPS)Infectious diseases and associated mortality have abated, but they remain a significant threat throughout the world.We continue to fight both old pathogens, such as the plague, that have troubled humanity for millennia and new pathogens, such as human immunodeficiency virus (HIV), that have mutated or spilled over ...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Active Citizens Development & Aid Economy & Trade Global Headlines Health TerraViva United Nations Source Type: news
Publication date: Available online 17 March 2018 Source:Microbes and Infection Author(s): Sagar B. Kudchodkar, Hyeree Choi, Emma L. Reuschel, Rianne Esquivel, Jackie Jin-Ah Kwon, Moonsup Jeong, Joel N. Maslow, Charles C. Reed, Scott White, J. Joseph Kim, Gary P. Kobinger, Pablo Tebas, David B. Weiner, Kar Muthumani Vaccines are considered one of the greatest advances in modern medicine. The global burden of numerous infectious diseases has been significantly reduced, and in some cases, effectively eradicated through the deployment of specific vaccines. However, efforts to develop effective new vaccines against infectious ...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
Publication date: Available online 17 March 2018 Source:Microbes and Infection Author(s): Sagar B. Kudchodkar, Hyeree Choi, Emma L. Reuschel, Rianne Esquivel, Jackie Jin-Ah Kwon, Moonsup Jeong, Joel N. Maslow, Charles C. Reed, Scott White, J. Joseph Kim, Gary P. Kobinger, Pablo Tebas, David B. Weiner, Kar Muthumani Vaccines are considered one of the greatest advances in modern medicine. The global burden of numerous infectious diseases has been significantly reduced, and in some cases, effectively eradicated through the deployment of specific vaccines. However, efforts to develop effective vaccines against infectious path...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
by Peter J. Hotez Within the last five years, the State of Texas has experienced either transmission or outbreaks of Ebola, chikungunya, West Nile, and Zika virus infections. Autochthonous transmission of neglected parasitic and bacterial diseases has also become increasingly reported. The rise of such emerging and neglected tropical diseases (NTDs) has not occurred by accident but instead reflects rapidly evolving changes and shifts in a “new” Texas beset by modern and globalizing forces that include rapid expansions in population together with urbanization and human migrations, altered transportation pa tter...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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