Neuromuscular effect of dexmedetomidine on sevoflurane: an open-label, dose-escalation clinical trial.

CONCLUSIONS: Sevoflurane has a concentration-dependent central neuromuscular effect in patients with normal neuromuscular transmission. Intravenous dexmedetomidine dose- dependently decreases the neuromuscular EC50 of sevoflurane. PMID: 28006886 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28006886?dopt=Abstract

Source: Minerva Anestesiologica - December 25, 2016 Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research