The effects of exogenous desmopressin on a model of heat stress nephropathy in mice.

CONCLUSIONS: Our studies document both glomerular and tubulointerstitial injury and inflammation in heat stress nephropathy, and may be clinically relevant to the pathogenesis of Mesoamerican Nephropathy. Our data also suggest that vasopressin may play a role in the pathogenesis of the renal injury of heat stress nephropathy, likely via a V2-receptor dependent pathway.
PMID: 28003190 [PubMed - as supplied by publisher]

Source: Am J Physiol Renal P... - December 20, 2016 Category: Urology & Nephrology Authors: Roncal-Jimenez CA, Milagres T, Andres-Hernando A, Kuwabara M, Jensen T, Song Z, Bjornstad P, Garcia GE, Sato Y, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ Tags: Am J Physiol Renal Physiol Source Type: research