Expression of ATPase inhibitory factor 1 in normal and pathological tissues of female reproductive system.

[Expression of ATPase inhibitory factor 1 in normal and pathological tissues of female reproductive system]. Nan Fang Yi Ke Da Xue Xue Bao. 2016 Dec 20;36(12):1626-1631 Authors: Zhao J, Liu X, Li YL Abstract OBJECTIVE: To determine ATPase inhibitory factor 1 (IF1) expression in normal and pathological tissue of female reproductive system to better understand the physiological role of IF1 in malignancies of the female reproductive system. METHODS: Surgical specimens of normal tissues and primary malignant tumors were obtained during the past 2 years, including 38 normal endometrium tissues, 33 endometriosis tissues, 30 endometrial adenocarcinoma tissues, 24 uterine myoideum tissues, 30 uterine fibroid tissues, 18 normal cervical tissues, 30 cervical squamous carcinoma tissues, 11 fallopian tube tissues, 19 fallopian tube adenocarcinoma tissues, 15 ovarian tissues, 21 ovarian endometrial adenocarinoma tissues, 30 decidua tissues, and 30 villus tissues. The expressions of IF1 protein and mRNA were assessed by immunohistochemistry, Western blotting and RT-PCR. RESULTS: The expressions of IF1 were significantly increased in endometrial adenocarcinoma (P
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

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