< i > Trypanosoma brucei < /i > Invasion and T-cell Infiltration of the Brain Parenchyma in Experimental Sleeping Sickness: Timing and Correlation with Functional Changes

ConclusionThese findings demonstrate invasion of the neuropil over time, after an initial interval, by parasites and lymphocytes crossing the blood-brain barrier, and show that neurological features can precede this event. The data thus challenge the current clinical and cerebrospinal fluid criteria of disease staging.

Source: PLoS Neglected Tropical Diseases - December 20, 2016 Category: Tropical Medicine Authors: Claudia Laperchia Source Type: research