' Incredibly Exciting': Diabetes Drug With CV Benefits'Incredibly Exciting': Diabetes Drug With CV Benefits

The FDA's recent addition of a cardiovascular indication for diabetes drug empagliflozin is a significant milestone in diabetes care, says Dr Anne Peters.Medscape Diabetes &Endocrinology
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology Commentary Source Type: news

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Metformin suppresses gastric cancer progression through calmodulin‑like protein 3 secreted from tumor‑associated fibroblasts. Oncol Rep. 2018 Oct 11;: Authors: Chen G, Yu C, Tang Z, Liu S, An F, Zhu J, Wu Q, Cao J, Zhan Q, Zhang S Abstract Gastric cancer is one of the most common malignant tumor types worldwide, with a high morbidity and associated mortality. The interaction between gastric cancer cells and their microenvironment has a significant role in their maintenance and progression. Gastric tumor‑associated fibroblasts (TAFs) are among the major regulators of the gastric cancer microe...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Peng S, Wei P, Lu Q, Liu R, Ding Y, Zhang J Abstract The effects of propolis on blood glucose regulation and the alleviation of various complications caused by diabetes have been widely studied. The main source of propolis in the northern temperate zone is poplar buds. However, there is limited research on the antidiabetic activity of poplar buds. In order to evaluate the effect of poplar buds on type-2 diabetes, crude extract and 50% fraction of poplar buds were used to feed streptozotocin-induced type-2 diabetic mice. The results showed that 50% fraction could increase insulin sensitivity and reduce insu...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
Microarray analysis reveals long non‑coding RNA SOX2OT as a novel candidate regulator in diabetic nephropathy. Mol Med Rep. 2018 Oct 04;: Authors: Zhang X, Shang J, Wang X, Cheng G, Jiang Y, Liu D, Xiao J, Zhao Z Abstract Diabetic nephropathy (DN) is a highly complex syndrome involving multiple dysregulated biological processes. Long non‑coding RNAs (lncRNAs) are now believed to have an important function in various diseases. However, their roles in DN remain largely unknown. Therefore, the present study was performed in order to investigate the lncRNAs that have a crucial role in DN. db/db mice we...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Tatiana Danilova, Maria Lindahl
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Conclusions: Findings from delivering the NDPP to diverse and undeserved patients show a large gap between service costs and projected reimbursement. Although many MDPP suppliers are needed to reach all Medicare beneficiaries with prediabetes, insufficient reimbursement may be a deterrent. Health disparities may also widen as suppliers serving diverse and low-income populations will likely receive especially low payments, threatening access. Higher payments are supported by strong return-on-investment findings and seem needed to reduce diabetes prevalence and related disparities.
Source: Medical Care - Category: Health Management Tags: Brief Report Source Type: research
TYPE 2 diabetes occurs when the level of sugar in the blood is too high. While this doesn ’t mean people with the condition have to completely avoid sugar, they should cut down on it. One easy way to do this is to swap fruit juice for whole fruits.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Carlos Guill én, Manuel Benito
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Journal of Cellular Biochemistry, EarlyView.
Source: Journal of Cellular Biochemistry - Category: Biochemistry Authors: Source Type: research
AbstractHeart rate variability (HRV) among other methods can be used to assess diabetic cardiac autonomic neuropathy by cardiac intervals were recorded. However, the amount of error depending on this measurement methodology is unclear. To evaluate the intra- and inter-rater reliability to calculate HRV indices, comparing different times and by different trained examiners in patients with type 2 diabetes mellitus (T2DM). Thirty individuals of both genders, aged between 18 and 45  years, with T2DM. The RR interval (RRi) were recorded during a 10 min period on supine position using a portable heart rate monitor (Pol...
Source: Journal of Medical Systems - Category: Information Technology Source Type: research
AbstractPurpose of ReviewIdiopathic pulmonary fibrosis (IPF) is an invariably progressive disease. Current treatment options simply slow disease progression, and better therapeutic options are needed. We aimed to review an emerging literature on risk factors associated with the development of IPF.Recent FindingsThere is increasing data to support the role of intrinsic risk factors (e.g., genetics, aging, sex, lung microbiome), comorbidities (e.g., gastroesophageal reflux, obstructive sleep apnea, diabetes mellitus, herpes virus infection), and extrinsic risk factors (e.g., cigarette smoking, environmental exposures, air po...
Source: Current Respiratory Care Reports - Category: Respiratory Medicine Source Type: research
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