Inhibiting the Migration of M1 Microglia at Hyperacute Period Could Improve Outcome of tMCAO Rats.

CONCLUSION: This study confirms the protective efficacy of inhibiting microglia migration at the hyperacute phase as a therapeutic strategy for ischemic stroke in tMCAO model of rats, and its therapeutic time window could last for 24 h after cerebral ischemia reperfusion. PMID: 27991729 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/27991729?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - December 18, 2016 Category: Neuroscience Authors: Huang M, Wan Y, Mao L, He QW, Xia YP, Li M, Li YN, Jin HJ, Hu B Tags: CNS Neurosci Ther Source Type: research