I-123-Metaiodobenzylguanidine imaging in patients with atrial fibrillation undergoing cardiac mapping and ablation of autonomic ganglia

The impact of ablation of ganglionated plexuses (GPs) during ablation of atrial fibrillation (AF) on ventricular myocardial innervation is unknown. Previous animal studies have shown different electrophysiological outcomes of ventricular myocardial denervation after ablation of autonomic ganglia.1,2 A recent animal report demonstrated that the ligament of Marshall could represent a conduit between the left stellate ganglion and the ventricle.2 There have been no reports evaluating detailed GP mapping and ablation in the atria and potential effects on ventricular sympathetic myocardial innervation.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research