DNA-Sensing and Nuclease Gene Expressions as Markers for Colorectal Cancer Progression

Conclusions: In contrast to DNA-sensing events in viral infections or autoimmunity,cGAS-STING-IFNB signaling is disrupted in colorectal cancer. The expression levels ofcGAS,RNASEH2B,RNASEH2C, andSAMHD1 could be prognostic markers of colorectal cancer.Oncology 2017;92:115-124
Source: Oncology - Category: Cancer & Oncology Source Type: research